Last edited by Viktilar
Sunday, May 10, 2020 | History

7 edition of Antisense Technology, Part A (Methods in Enzymology, Volume 313) (Methods in Enzymology) found in the catalog.

Antisense Technology, Part A (Methods in Enzymology, Volume 313) (Methods in Enzymology)

  • 348 Want to read
  • 14 Currently reading

Published by Academic Press .
Written in English

    Subjects:
  • Enzymology,
  • Genetics (non-medical),
  • Genetic Research,
  • Rna (Ribonucleic Acid),
  • Science,
  • Medical / Nursing,
  • Medical,
  • Biochemistry,
  • Life Sciences - Biochemistry,
  • Life Sciences - Biology - General,
  • Science / Biology,
  • Life Sciences - Genetics & Genomics

  • Edition Notes

    ContributionsJohn N. Abelson (Editor), Melvin I. Simon (Editor), Ian M. Phillips (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages576
    ID Numbers
    Open LibraryOL9369624M
    ISBN 100121822141
    ISBN 109780121822149

    Antisense therapies change the process of producing a protein before it even begins. To build a protein, a cell must make a copy of the DNA, which contains specific instructions for how to make that particular protein. This copy, called messenger RNA (mRNA), carries the instructions to the part of the cell where proteins are made. Antisense technology. Part B, Applications. [M Ian Phillips;] Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. Book, Internet Resource: All Authors / .

    Get this from a library! Antisense technology. [M Ian Phillips;] -- Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example.   This state-of-the-art reference provides comprehensive coverage of the development of antisense oligonucleotides to inhibit cancer cells as well as those involved in infectious, inflammatory, and immune-mediated diseases-highlighting new tools and technologies in medicinal chemistry, RNA biochemistry, and molecular and cellular biology to produce new therapeutic ts Reviews: 1.

    Therapeutic Application of Antisense Technology. A second application of this technology, and one that is potentially of more immediate relevance to the practicing physician, is the use of this technology in therapy ().In principle, antisense oligonucleotides complementary to viral RNAs can suppress a wide variety of viral infections; a tremendous amount of research is ongoing in this by: 2. Antisense therapy is a form of treatment for genetic disorders or infections. When the genetic sequence of a particular gene is known to cause a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue) that will bind to the messenger RNA (mRNA) produced by that gene and inactivate it, effectively turning that gene "off".


Share this book
You might also like
Points for Emphasis, 1995-96

Points for Emphasis, 1995-96

Pocket pal

Pocket pal

Dostoevsky and Andreyev

Dostoevsky and Andreyev

Isle of view

Isle of view

The Food of the Gods

The Food of the Gods

France.

France.

Topics in critical point theory

Topics in critical point theory

Introduction to the science of law

Introduction to the science of law

Public laws of the state of New-York

Public laws of the state of New-York

Greek cook book

Greek cook book

Words or vision

Words or vision

Low cost bridge deck surface treatment.

Low cost bridge deck surface treatment.

Physical geography

Physical geography

Antisense Technology, Part A (Methods in Enzymology, Volume 313) (Methods in Enzymology) Download PDF EPUB FB2

Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies (ISSN Book ) - Kindle edition by Abelson, John N., Simon, Melvin I., Phillips, M. Ian. Download it once and read it on your Kindle device, PC, phones or tablets. Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation.

For example, methods that inhibit gene expression permit studies which probe Format: Hardcover. Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies, Volume (Methods in Enzymology) () [unknown] on *FREE* shipping on qualifying offers. Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies, Volume (Methods in Enzymology) (): unknown: Antisense Technology Books.

Antisense Technology, Part A (Methods in Enzymology, Volume ) (Methods in Enzymology) [Academic Press] on *FREE* shipping on qualifying : Academic Press. Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study Antisense Technology gene function and gene regulation.

For example, methods that inhibit gene expression permit studies which probe. This book fulfils such expectations by providing clear and precisely described protocols Antisense Technology offers potential for therapy and for the study of gene roles through the development of specific agents that can modulate the function of the genes or their proteins.

The experience gained from experimental and clinical trials in the antisense area has been concentrated in this book which Format: Paperback. Antisense Technology Part A: General Methods, Methods of Delivery, and RNA Studies.

Antisense technology is a powerful procedure that permits the controlled silencing of a specific gene for investigations of mRNA and protein function. This valuable text provides proven step-by-step protocols for antisense techniques in a range of different organisms and cell culture addition it discusses the potential benefits and problems for various antisense methods which.

Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research.

Interpreting lessons learned from the clinical trials of first generatiCited by:   Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation.

For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a Edition: 1. Antisense technology as a powerful tool for regulating gene expression owes a great deal to inventions of various chemical modifications that confer drug-like properties to single-stranded oligonucleotides.

Some of these modifications stabilize the ASOs by protecting them from exonucleases and endonucleases, or they protect the target RNA from RNase H, which cleaves RNA in RNA–DNA hybrids. Antisense technology. Part A, General methods, methods of delivery and RNA studies. Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation.

Part A, General methods, methods of delivery and RNA studies\/span>\n. Antisense technology. Part A, General methods, methods of delivery and RNA studies [Ressource électronique] / edited by M. Ian Phillips Amsterdam: Elsevier, cop. (@Methods in enzymology) (ABES)X: Material Type: Internet resource: Document Type: Book.

Investments in Antisense Technology LIVER SPLEEN FAT BONE MARROW ASO-KIDNEYS ASO A, 4 µg, n=24, 25d ISIS SMN Rx Increases Survival in a Mouse Model of SMA Improves Muscle Health A K nown Biological T argets Year Genomic Revolution Addition of non-coding RNAs Gene mRNA DISEASE Transcription anslation.

Book Description. Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research.

Interpreting lessons learned from the clinical trials of first generation drugs, the book evaluates the. Description: Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation.

For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. UGCA5’ Antisense RNA. This article gives brief introduction regarding the antisense technology. Keywords: Antisense technology, protein production, gene expression. INTRODUCTION Diseases are often connected to the insufficient or excess production of certain “Proteins”.

If the production of these proteins is disputed many diseases can be File Size: KB. Part of the Methods in Molecular Biology book series (MIMB, volume ) Abstract Advances in molecular biology and genetics have been used to elucidate the fundamental genetic mechanisms underlying central nervous system (CNS) diseases, yet disease-modifying therapies are currently unavailable for most CNS by: 9.

Antisense RNA consists of sequences complementary to a target RNA and can act as a regulatory molecule by binding to the target species via base pairing. Gene expression can be inhibited in this manner; such regulation occurs naturally in bacteria and has been demonstrated experimentally in eukaryotes (for reviews see 1–6).Cited by: 8.

Antisense technology can be used for producing decorative plants exhibiting one or more desired phenotypic traits by manipulating genes involved in flavonoid biosynthetic pathway (Figure a).

Antisense Technology Part B: Applications. M. Ian Phillips. VolumePages () Show all chapter previews Show all chapter previews.

Receive an update when the latest chapters in this book series are published. Sign in to set up alerts. select article Contributors to volume [24] Antisense methods for discrimination of.

Antisense therapeutics is well positioned to play a significant role in the progression of antisense technology for drug development in human diseases. However, proof of clinical efficacy, of any of the antisense oligonucleotides in the field of oncology, is still missing.Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research.

Interpreting lessons learned from the clinical trials of first generation drugs, the book evaluates the technology as a.